Etiology of TP53 mutated complex karyotype acute myeloid leukemia.

ABSTRACT: SCHEMATIC VIEW OF THE DEVELOPMENT OF CK-AML DRIVEN BY THE TP53 ABSENCE.: The occurrence of the first, often dominant negative TP53 mutation is quickly followed by the loss of the second TP53 allele and numerous further chromosomal aberrations.

SUBMITTER: Fedenko A 

PROVIDER: S-EPMC12875860 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature