Type 2 diabetes is associated with pulmonary cavitation in men with HIV-TB coinfection.

ABSTRACT:

Objectives

To explore the association between type 2 diabetes mellitus (T2D) and pulmonary cavitation in male with HIV-tuberculosis (TB) coinfection, as well as to quantify the relationships between glycemic indicators [HbA1c and fasting plasma glucose (FPG)] and cavity size. The robustness of these correlations was further validated in a non-HIV TB sample.

Methods

This comparative cross-sectional study based on exposure status included 132 men with HIV-TB and T2D (exposed group) and 131 age-matched men with HIV-TB without T2D (non-exposed group). Multivariable regression models, subgroup analyses, and interaction tests were used to evaluaterelationships and effect modification. A validation cohort of 100 non-HIV TB patients was analyzed using the same analytical framework.<

SUBMITTER: Mao Y 

PROVIDER: S-EPMC12875991 | biostudies-literature | 2026

REPOSITORIES: biostudies-literature