Ontology highlight
ABSTRACT:
SUBMITTER: Yoon JH
PROVIDER: S-EPMC12876103 | biostudies-literature | 2026 Feb
REPOSITORIES: biostudies-literature

Annals of hematology 20260205 3
Inotuzumab ozogamicin (InO), a CD22-targeted antibody-drug conjugate, delivers the cytotoxic agent, calicheamicin, to B-cell precursor of relapsed or refractory B-cell precursor acute lymphoblastic leukemia (R/R B-ALL) cells. It has demonstrated efficacy in phase 3 trials, leading to approval in multiple countries, including the U.S., Japan, and South Korea. In our post-marketing surveillance (PMS) study, we evaluated the safety and effectiveness of InO in adults with R/R B-ALL based on approxim ...[more]