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Real-world outcomes of inotuzumab ozogamicin treatment for adult relapsed or refractory acute lymphoblastic leukemia: a result from Korea post-marketing surveillance.


ABSTRACT:

SUBMITTER: Yoon JH 

PROVIDER: S-EPMC12876103 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature

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Real-world outcomes of inotuzumab ozogamicin treatment for adult relapsed or refractory acute lymphoblastic leukemia: a result from Korea post-marketing surveillance.

Yoon Jae-Ho JH   Lee Jung-Hee JH   Yang Deok-Hwan DH   Cheong June-Won JW   Byun Ja Min JM   Yoo Kwai Han KH   Woo Juwon J   Kim Young-Mee YM   Lee Seok S  

Annals of hematology 20260205 3


Inotuzumab ozogamicin (InO), a CD22-targeted antibody-drug conjugate, delivers the cytotoxic agent, calicheamicin, to B-cell precursor of relapsed or refractory B-cell precursor acute lymphoblastic leukemia (R/R B-ALL) cells. It has demonstrated efficacy in phase 3 trials, leading to approval in multiple countries, including the U.S., Japan, and South Korea. In our post-marketing surveillance (PMS) study, we evaluated the safety and effectiveness of InO in adults with R/R B-ALL based on approxim  ...[more]

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