Laparoscopic versus open pancreatoduodenectomy: a pilot randomized trial in a developing African country.

ABSTRACT:

Background

Pancreatoduodenectomy (PD) is a major abdominal surgery. While laparoscopic PD (LPD) is gaining acceptance globally, its feasibility and safety in low-resource settings require further evaluation. This study aimed to identify the benefits and drawbacks of LPD compared to open PD (OPD) in a developing African country.

Patients and methods

This randomized controlled trial included patients with oncologic indications for PD. Participants were randomized into two groups: LPD and OPD. The primary endpoint was length of hospital stay, postoperative morbidity and mortality, blood loss, and the need for transfusion of blood products. The secondary outcomes were the operative time in minutes, pain VAS scores, duration to ambulation, gastrointestinal (GIT) recovery, and the

SUBMITTER: Mostafa MS 

PROVIDER: S-EPMC12881053 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature