Meta-analysis for the associations of serum C-reactive protein with delirium risk.

ABSTRACT:

Background

This meta-analysis aimed to evaluate the association between serum C-reactive protein (CRP) levels and delirium risk, encompassing postoperative delirium (POD) and delirium secondary to other medical conditions.

Methods

A systematic search was conducted across PubMed, Web of Science, and the Chinese National Knowledge Infrastructure database. The odds ratio (OR) with their 95% confidence intervals (CI) from each study were extracted and used to estimate the effects. Meta-regression analysis was utilized to identify potential sources of heterogeneity. Subgroup analyses were applied to explore the association under different disease types (POD vs. non-POD), and age groups (>70 years or ≤70 years) among delirium patients.

Results

A total of 9,002 patients from

SUBMITTER: Liang QX 

PROVIDER: S-EPMC12893975 | biostudies-literature | 2026

REPOSITORIES: biostudies-literature