Novel use of <i>Quillaja saponaria</i> extracts to prevent viral infections in Atlantic salmon: <i>in vitro</i> ISAv and IPNv inhibition and <i>in vivo</i> protection against IPNv.

ABSTRACT:

Introduction

The global expansion of salmon farming has increased the prevalence of viral diseases, especially Infectious Pancreatic Necrosis (IPN) and Infectious Salmon Anemia (ISA), posing significant threats to the sustainability and productivity of the industry. Extracts from the Chilean tree Quillaja saponaria Molina are a rich source of triterpenic saponins, glycosides with antimicrobial and immunomodulatory properties. This study assessed the antiviral efficacy of a non-purified (NPQ), a partially purified (PPQ, the active ingredient of PAQ-Xtract®), and a purified (VaxSap®) commercial Quillaja saponaria extracts, as dietary additives to prevent and control viral infections in Atlantic salmon (Salmo salar).

Methods

The In vitro antiviral ac

SUBMITTER: Schlotterbeck T 

PROVIDER: S-EPMC12894021 | biostudies-literature | 2026

REPOSITORIES: biostudies-literature