Association between endothelial function and early neurological improvement in atrial fibrillation-related ischemic stroke.

ABSTRACT:

Background

Understanding the factors related to early neurological improvement (ENI) is crucial in managing atrial fibrillation-related ischemic stroke (AF-stroke), as ENI indicates better long-term outcomes. We investigated the association between endothelial function, measured via flow-mediated dilation (FMD), and the occurrence of ENI in patients with AF-stroke.

Methods

We reviewed patients with acute AF-stroke within 7 days of FMD between April 2019 and April 2025. ENI was defined as a ≥2-point decrease in National Institutes of Health Stroke Scale (NIHSS) or ≥1-point reduction in motor NIHSS items within 24 h in non-thrombolysis patients. For thrombolysis patients, ENI was a ≥8-point reduction or NIHSS 0-1 at 24 h. FMD was measured during hospitalization and expressed a

SUBMITTER: Yang SY 

PROVIDER: S-EPMC12894233 | biostudies-literature | 2026

REPOSITORIES: biostudies-literature