Does Mirikizumab benefit patients with plaque psoriasis? a systematic review and meta-analysis.

ABSTRACT:

Background

Plaque psoriasis is a chronic skin condition characterized by skin scales. It causes a cosmetic problem for patients. Mirikizumab has shown promising results in managing psoriasis. Nevertheless, there remains a dispute over its safety. This systematic review and meta-analysis aimed to assess the effectiveness of mirikizumab in individuals with plaque psoriasis.

Methods

We searched four databases: PubMed, Scopus, Cochrane CENTRAL, and Web of Science. We included trials comparing mirikizumab with placebo in psoriatic patients. Two independent authors extracted data in an Excel sheet. We used RevMan software (version 5.2) to perform meta-analysis.

Results

A meta-analysis of three RCTs with a total of 1648 patients was performed. Mirikizumab showed significantl

SUBMITTER: Mohamed SF 

PROVIDER: S-EPMC12894435 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature