Effects of multidomain intervention on cognitive function in older adults with cognitive impairment: A multicenter, four-arm, cluster randomized trial.

ABSTRACT:

Introduction

Multidomain lifestyle-based interventions seem to be effective for cognitive improvement but larger trials are limited, especially in China. This study aims to explore whether multi-domain interventions of Baduanjin exercise, the Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet, and relaxation training can improve cognitive function in older adults.

Methods

This is a four-arm cluster randomized trial conducted in 15 centers (counties/districts) in China. A total of 60 communities with 886 older adults with cognitive impairment were randomized to the control group (routine service, RS), and groups B (Baduanjin exercise, plus RS), BM (Baduanjin exercise and MIND diet, plus RS), and BMR (Baduanjin exercise, MIND diet, and relaxation training,

SUBMITTER: Yin Z 

PROVIDER: S-EPMC12895087 | biostudies-literature | 2026 Jan-Mar

REPOSITORIES: biostudies-literature