Prognostic Value of Qualitative Splenic [¹⁸F]FDG Uptake on Baseline PET/CT in Newly Diagnosed Diffuse Large B-Cell Lymphoma.

ABSTRACT: Background/Objectives: Accurate risk stratification at diagnosis is crucial for the optimal management of diffuse large B-cell lymphoma (DLBCL). While Fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography ([¹⁸F]FDG PET/CT) is the standard imaging modality for staging, the prognostic value of non-tumoral uptake patterns remains under investigation. Here, we aimed to investigate the prognostic significance of qualitative splenic [¹⁸F]FDG uptake on baseline PET/CT in patients with newly diagnosed DLBCL, focusing on relapse-free survival (RFS) and overall survival (OS). Methods: This retrospective study included consecutive patients with newly diagnosed DLBCL in a Korean cohort who underwent baseline [¹⁸F]FDG PET/CT betwe

SUBMITTER: Hwang Y 

PROVIDER: S-EPMC12896426 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature