Mid-Term Outcomes, Biological Responses and Complications of Dental Implants in Maxillomandibular Reconstruction with Free Bone Flaps: A Systematic Review and Meta-Analysis.

ABSTRACT: Background/Objectives: Maxillofacial reconstruction with a vascularized free bone flap for facial contour restoration serves as a foundation for dentition rehabilitation. Although state-of-the-art studies have reported promising results with implant-supported prostheses in such cases, evidence for dental implant prognosis remains insufficient. This study aims to synthesize the mid-term clinical outcomes of implants placed in vascularized free bone flaps, taking into account the biological responses and associated complications. Methods: Studies with a minimal 3-year follow-up, no less than 10 patients, and reporting implant survival/success rate were included. Literature published from 2000 to 2025 was collected from PubMed, Embase, and Scopus. Meta-analyses were performed to

SUBMITTER: Qiu S 

PROVIDER: S-EPMC12896764 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature