Clinical Profile of a Series of Left-Sided Prosthetic Valve Endocarditis: Revisiting Surgical Indications.

ABSTRACT: Background/Objectives: Prosthetic valve endocarditis (PVE) carries a high morbidity and mortality. Surgery is classically indicated for heart failure, uncontrolled infection, or prevention of embolic events; however, evidence supporting surgery for "non-classical" indications-such as Staphylococcus aureus infection, non-HACEK Gram-negative bacteria, or early PVE-remains limited. This study aimed to update the clinical and prognostic profile of PVE and assess the impact of surgery, particularly in patients with non-classical surgical indications. Methods: We prospectively included all definite left-sided PVE cases diagnosed between 2000 and 2024 at three tertiary centers. Clinical, microbiological, echocardiographic, and prognostic data were analyzed and compared. Predi

SUBMITTER: Ibanez AL 

PROVIDER: S-EPMC12897040 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature