Diagnostic Limitations, Patient Characteristics, and Confounding Factors Impacting Neurotologic Lesion Imaging: A Systematic Review.

ABSTRACT: Background: Neuroimaging protocols for neurotologic disease are often developed without consideration of patient-specific factors such as biological differences, clinical presentation variability, and comorbidities. This lack of tailored design contributes to insufficient detection, delayed diagnosis, and inappropriate treatment. Objectives: To critically examine the literature on diagnostic limitations of neuroimaging for neurotologic lesions and identify gaps in protocol validation, accuracy, and clinical translation. Methods: A systematic review of PubMed and Google Scholar was conducted, focusing on studies published between 2015 and 2025 that evaluated diagnostic imaging outcomes in patients with neurotologic lesions. Eligible studies included prospective cohorts,

SUBMITTER: Hamdan D 

PROVIDER: S-EPMC12897181 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature