Evaluation of the Performance of Novel Gram-Negative and Gram-Positive Sepsis Panels for the Rapid Diagnosis of Bloodstream Infections.

ABSTRACT: Background/Objectives: Bloodstream infections (BSIs) are a global healthcare issue associated with high mortality rates. Rapid diagnosis is of importance for the early selection of targeted therapy to improve patient outcomes. The use of rapid molecular assays with positive blood culture (BC) allows the identification (ID) of pathogens and the most relevant resistance determinants (RDs) in a shorter turnaround time, compared to standard culture. In this study, the performances of a new syndromic panel to determine the IDs and RDs of Gram-negative (GN) and Gram-positive (GP) bacteria were investigated in comparison with a standard-of-care (SoC) workflow. Methods: Two hospitals processed residual positive BC samples from non-replicated patients using Molecular Mouse (MM) Sepsis

SUBMITTER: Chilleri C 

PROVIDER: S-EPMC12897205 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature