Dialdehyde Alginate as a Crosslinker for Chitosan/Starch Films: Toward Biocompatible and Antioxidant Wound Dressing Materials.

ABSTRACT: Biopolymer-based films have attracted increasing attention as sustainable and bioactive materials for wound management. Among them, chitosan (CTS) and starch (ST) blend represent promising candidate due to their natural origin, biodegradability, and intrinsic biological activity; however, their mechanical weakness and limited stability necessitate additional modification. This study reports the development and characterization of CTS-ST thin films crosslinked with dialdehyde alginate (ADA), synthesized via controlled oxidation. Two ADA variants differing in aldehyde group content were prepared to investigate the effect of crosslinking on the structural, physicochemical, and biological performance of the materials. The films were fabricated by blending 2% w/v CTS and ST in var

SUBMITTER: Grabska-Zielinska S 

PROVIDER: S-EPMC12897587 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature