Point-of-Care Bilirubin Testing in Neonates: Comparative Performance of Blood Gas Analysis and Transcutaneous Bilirubinometry.

ABSTRACT: Background: Neonatal jaundice is a common condition with potentially severe complications such as bilirubin-induced neurological dysfunction and kernicterus. While serum bilirubin (SBR) remains the standard laboratory measurement, point-of-care methods, such as transcutaneous bilirubinometry (TcB) and blood gas analysers (BGAs), offer rapid, less invasive alternatives. Direct comparisons of their diagnostic accuracy remain limited. Objective: The aim of this study was to assess and compare diagnostic accuracy and clinical utility of TcB and BGA against SBR in neonatal hyperbilirubinaemia screening. Methods: This retrospective study included neonates (n = 221) with concurrent SBR, BGA, and TcB measurements (n = 333). Assessment was via Passing-Bablok regression, Bland-A

SUBMITTER: Xu A 

PROVIDER: S-EPMC12897715 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature