Efficacy of Resin Infiltrants in Non-Cavitated Occlusal Carious Lesions: A Systematic Review.

ABSTRACT: Objectives: To evaluate the efficacy of resin infiltrants (RIs) in controlling non-cavitated occlusal carious lesions (NCOCLs) in primary and permanent teeth. Methods: This systematic review followed PRISMA guidelines. Randomized clinical trials (RCTs) and in vitro/ex vivo studies comparing RI with placebo or other materials were included. Searches were conducted in five databases and gray literature up to December 2025. Risk of bias was assessed using the RoB 2.0 tool for RCT and an adapted instrument for in vitro/ex vivo studies. Certainty of evidence was evaluated using the GRADE tool, and data were synthesized qualitatively. Results: Eight studies were included, of which only two were RCTs, and six were in vitro and ex vivo studies. RCTs showed reduced caries progr

SUBMITTER: Miranda SB 

PROVIDER: S-EPMC12897895 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature