Comparison of Heart Failure Hospitalizations with and Without Respiratory Syncytial Virus: A Nationwide Administrative Data Analysis.

ABSTRACT: Background: Heart failure (HF) remains a major cause of hospitalizations in the United States (US). Respiratory syncytial virus (RSV) has been associated with HF exacerbations. We compared in-hospital outcomes and healthcare utilization among US HF hospitalizations with and without RSV. Methods: Using the Nationwide Readmissions Database (2016-2022), we propensity-matched HF hospitalizations with a secondary diagnosis of RSV (HF-RSV) 1:1 to those without RSV (HF-noRSV). Multivariable logistic and Poisson regression models were used to assess associations between RSV and outcomes. The primary outcome was in-hospital mortality; secondary outcomes included adverse events, length of stay (LOS), hospitalization costs, and 30-day readmissions. Results: Among 11,158,836 HF ho

SUBMITTER: Patil N 

PROVIDER: S-EPMC12898105 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature