Predictors and Prognostic Significance of Appropriate Implantable Cardioverter-Defibrillator Therapy in Primary Prevention Patients with Ischemic Cardiomyopathy.

ABSTRACT: Background: In the population of patients with ischemic cardiomyopathy (IC) and reduced left ventricular ejection fraction, the benefits of prophylactic implantable cardioverter-defibrillator (ICD) therapy are not uniform. Identifying predictors of ventricular arrhythmias to estimate the risk of appropriate therapy is crucial. Methods: Patients with IC and an ICD for primary prevention implanted between 2006 and 2019 were retrospectively analyzed for appropriate therapy (ATh). The primary objective was to assess predictors of ATh development. The secondary objective was to assess the impact of ATh on survival. Results: Overall, 260 patients (age 67.3 ± 9.4 years, 15.4% female) were analyzed with a follow-up of 4.47 ± 3.02 years. ATh occurred in 79 patients (30.4% of th

SUBMITTER: Kusmierz M 

PROVIDER: S-EPMC12898167 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature