Association Between Donor Kidney Function and Post-Transplant Graft Function in Deceased-Donor Kidney Transplantation.

ABSTRACT: Background/Objectives: Donor kidney function measured by glomerular filtration rate (GFR) is widely used as a selection criterion in kidney transplantation (KT). This study addresses the knowledge gap regarding the relationship between donor GFR at organ procurement and graft function in deceased donor KT. Methods: We retrospectively analyzed 918 deceased donor KTs and compared donor GFRs at procurement and recipient GFRs after KT at hospital discharge and in the one-year follow-up. The Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) formula was used to estimate and compare GFRs. Donor baseline GRF was defined as the last available estimated GRF prior to organ procurement. The Kaplan-Meier analysis was used to estimate recipient and graft survival. Results:

SUBMITTER: Pezeshk AS 

PROVIDER: S-EPMC12898353 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature