Associations of FTO and CLOCK Genetic Variants with Emotional Eating and Reward-Related Appetite Regulation Among Healthy Young Adult Males: An Exploratory Secondary Analysis.

ABSTRACT: Background: Patterns of dysregulated eating, including overeating, frequent snacking, and heightened food cravings, are associated with an increased risk of obesity and metabolic disease. Eating behaviors are multidimensional and can influence many factors, including social, cultural, and biological processes. Emerging evidence suggests that genetic variation may contribute to inter-individual differences in appetite regulation and reward-related eating, potentially influencing susceptibility to dysregulated eating patterns and behaviors. Objectives: This exploratory, secondary analysis investigated possible relationships between the genetic variants FTO rs9939609, CLOCK rs1801260, MC4R rs17782313, and CD36 rs1761667 and eating behavior traits and postprandial appetite regula

SUBMITTER: Brown JE 

PROVIDER: S-EPMC12899139 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature