Exploring <i>Castanea sativa</i> Shells (CSSs) as a Source of AKR1B1 and AKR1B10 Inhibitors: From Extraction to Bioactivity Testing.

ABSTRACT: Chestnut shells are widely recognized as a source of bioactive compounds, including polyphenols and other antioxidant molecules. The industrial chestnut food chain generates large amounts of this by-product, which represents both a waste disposal challenge and a potential source of promising biomolecules. Thermal treatments occurring during industrial processing, however, may affect both chemical composition and bioactivity. Characterization of the chemical composition and biological activity of chestnut shells can contribute to the valorisation of this industrial by-product. Understanding which molecular alterations are caused by the processing is essential to assess the real potential of chestnut shell biomass. This study provides a comparative analysis of Castanea sativa shells,

SUBMITTER: Piazza L 

PROVIDER: S-EPMC12899490 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature