Comparative Effectiveness of Behavioural Sodium-Reduction Interventions for Intensive Systolic Blood Pressure Control in Populations with Elevated Blood Pressure: A Systematic Review and Network Meta-Analysis.

ABSTRACT: Background: Globally, an estimated 1.4 billion people had hypertension in 2014, yet only just over 20% had controlled blood pressure, and about 580 million remained undiagnosed. Evidence indicates that salt substitutes facilitate meaningful blood-pressure reductions, yet their implementation remains restricted by social and healthcare constraints. The comparative effectiveness of alternative sodium-reduction interventions for elevated blood pressure remains unclear, limiting their introduction across diverse clinical and public health contexts. This study is registered with PROSPERO (CRD420251130153). Methods: We systematically searched PubMed, MEDLINE, and supplementary sources for randomised controlled trials (RCTs) published between 2000 and 2025. All behavioural sodium-re

SUBMITTER: Prommas P 

PROVIDER: S-EPMC12899601 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature