Process Evaluation of a Time-Restricted Eating Intervention for Weight Management in South African Women Living with Overweight/Obesity and HIV on Dolutegravir-Based Antiretroviral Therapy: A Qualitative, RE-AIM-Informed Analysis.

ABSTRACT: Background: South Africa faces the world's highest HIV burden, disproportionately affecting women, alongside rising Type 2 Diabetes (T2D). Weight gain associated with preferred dolutegravir (DTG)-based antiretroviral therapy may worsen obesity and T2D risk. This process evaluation explored the implementation of a 12-month time-restricted eating (TRE) intervention for weight management in women with HIV and overweight/obesity in Khayelitsha, Cape Town. Methods: Using the RE-AIM framework, the study investigated the implementation journey. Data were collected from three groups: RCT participants, healthcare workers (n = 21), and fieldworkers (n = 3). Methods included structured informal interviews with TRE participants throughout the intervention and semi-structure

SUBMITTER: Hoosen F 

PROVIDER: S-EPMC12899678 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature