Bioelectrical Impedance and GLIM Criteria Identify Early Nutritional Deterioration and Mortality in Acute Leukemia Patients Undergoing Chemotherapy.

ABSTRACT:

Background/objectives

Malnutrition is highly prevalent in patients with acute leukemia and is frequently underrecognized at diagnosis. Traditional screening tools based on anthropometry often fail to identify early nutritional deterioration. This study aimed to evaluate the prognostic utility of a comprehensive morphofunctional assessment-including bioelectrical impedance vector analysis (BIVA), handgrip strength (HGS), and muscle ultrasound-conducted at diagnosis and after induction therapy, to evaluate the prognostic association with 12-month mortality.

Methods

In this prospective cohort study, 52 adult patients with newly diagnosed acute leukemia were enrolled between November 2022 and November 2024 at two tertiary hospitals in Málaga, Spain. Nutritional status was determ

SUBMITTER: Dalla Rovere L 

PROVIDER: S-EPMC12899684 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature