Patterns and risk of cardiovascular disease in rheumatoid arthritis and psoriatic arthritis: a nationwide cohort study in the UK.

ABSTRACT:

Objective

Patients with inflammatory arthritis (IA), including RA and PsA, have an elevated cardiovascular disease (CVD) risk. It is unclear whether this persists in the modern treat-to-target era, particularly in early disease. This study evaluates CVD risk and mortality in a contemporary early RA and PsA cohort.

Methods

Adults (≥18 years) with newly diagnosed RA or PsA registered in the National Early Inflammatory Arthritis Audit (NEIAA) from 2018 to 2023 were included. Incidence rates of CVD events, major adverse cardiovascular events (MACE) and all-cause and CVD mortality were calculated. Standardized incidence and mortality ratios compared outcomes with the general population. Competing risk regression assessed factors associated with CVD outcomes.

Results

A tota

SUBMITTER: Yang Z 

PROVIDER: S-EPMC12900542 | biostudies-literature | 2026

REPOSITORIES: biostudies-literature