AI-assisted interpretation of bone scans: Performance comparison between ChatGPT-4o and a TFDA-approved bone scintigraphy platform in AI-driven nuclear imaging interpretation.

ABSTRACT:

Background

With the emergence of artificial intelligence in medical imaging, large language models such as chat generative pre-trained transformer (ChatGPT)-4o have drawn much attention for their potential in diagnostic support. However, their performance in nuclear medicine applications still remains underexplored. In this study, we aimed to evaluate the Taiwan Food and Drug Administration (TFDA)-approved bone scintigraphy (BS platform) and ChatGPT-4o capability to interpret BS images for the detection and localization of bone metastases.

Methods

A total of 52 BS images were analyzed with three interpretation methods: board-certified physicians, ChatGPT-4o multimodal image analysis, and the BS platform. The performance of the interpretations was evaluated with both binary c

SUBMITTER: Lee YY 

PROVIDER: S-EPMC12901947 | biostudies-literature | 2026 Jan-Dec

REPOSITORIES: biostudies-literature