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Early Percutaneous Kyphoplasty Is Associated with Reduced Risk of Subsequent Thoracic Vertebral Compression Fracture.


ABSTRACT:

Introduction

Although percutaneous kyphoplasty (PKP) is widely recognized as an effective treatment for osteoporotic vertebral compression fractures (VCFs), there is growing concern about the risk of subsequent VCF after the procedure. Prior studies suggest that the timing between primary VCF and PKP may affect future VCF, but there are limited data evaluating this timing, and no studies use data-driven methods to derive precise thresholds. Therefore, the aim of this study was to determine (1) the optimal time interval that minimizes the risk of 2-year subsequent VCF and (2) the impact of this interval on 90-day medical complications after PKP.

Methods

A retrospective cohort analysis in patients who underwent PKP for primary thoracic VCF from 2010 to 2022 was identified usin

SUBMITTER: Ramesh A 

PROVIDER: S-EPMC12902211 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature