Myocardial fibrosis predicts sudden cardiac death in patients with hypertrophic cardiomyopathy after cardiac electronic device implantation: Insights from cardiovascular magnetic resonance imaging.

ABSTRACT:

Background

Patients with hypertrophic cardiomyopathy (HCM) face an increased risk of sudden cardiac death (SCD), and myocardial fibrosis is predictive of ventricular arrhythmias.

Objective

This study aimed to determine whether the location, pattern, and quantification of myocardial fibrosis predict SCD in patients with HCM after cardiac implantable electronic device (CIED) implantation.

Methods

This study included patients with HCM who completed cardiovascular magnetic resonance and received CIED between June 2017 and January 2023. The primary outcome was SCD or SCD-equivalent events (composite of SCD, resuscitated cardiac arrest, sustained ventricular tachycardia or ventricular fibrillation, or appropriate implantable cardioverter-defibrillator therapy).

Results</

SUBMITTER: Fu B 

PROVIDER: S-EPMC12902231 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature