Body Composition in Resectable Non-Small Cell Lung Cancer Patients With Preoperative Sarcopenia: A Propensity-Matched Analysis.

ABSTRACT:

Background

Sarcopenia is a prognostic factor in patients with early-stage non-small cell lung cancer (NSCLC). Previous studies have focused on muscle loss, yet comprehensive body composition (BC) alterations in this population remain poorly characterized. This study aimed to delineate BC alterations using bioelectrical impedance analysis (BIA) in early-stage NSCLC patients with preoperative sarcopenia, with a specific focus on sex-specific disparities and the identification of independent BC factors associated with sarcopenia.

Methods

In this case-control study, 460 patients with Stage I-II NSCLC were initially enrolled from two tertiary hospitals in Anhui, China. Sarcopenia was diagnosed preoperatively based on Asian Working Group for Sarcopenia 2019 criteria. Multifrequenc

SUBMITTER: Wang ZZ 

PROVIDER: S-EPMC12902443 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature