Safety and feasibility of the treatment of calcified <i>de novo</i> coronary artery lesions with drug-coated balloon angioplasty after intravascular lithotripsy.

ABSTRACT:

Objectives

Percutaneous coronary intervention (PCI) of calcified lesions using stenting may lead to stent malapposition and stent underexpansion. The combination of intravascular lithotripsy (IVL) followed by drug-coated balloon (DCB) treatment may help overcome this limitation. The aim of this single-center, retrospective, registry-based observational study was to assess the efficacy and safety of plaque modification using IVL followed by DCB-only treatment in patients with severely calcified lesions.

Methods

Severely calcified de novo coronary artery lesions were prepared using IVL followed by the application of paclitaxel-coated DCB in 34 consecutive patients; five patients requiring bail out stenting were excluded from the analysis. The cohort included patients bo

SUBMITTER: Rasanen A 

PROVIDER: S-EPMC12902940 | biostudies-literature | 2026

REPOSITORIES: biostudies-literature