Association between neighborhood-level overall social vulnerability and cumulative incidence of reported hepatitis C virus infection in Los Angeles County from 2018 to 2023.

ABSTRACT:

Background

Hepatitis C is a serious public health problem in Los Angeles County. Only 30% of diagnosed persons are treated, and transmission is increasing. To further understand how social determinants impact hepatitis C, we assessed the association between neighborhood-level socioeconomic factors and the reported incidence of hepatitis C infection.

Methods

We conducted an ecological study of Los Angeles County residents aged 18 to 29 years with a reported positive hepatitis C viral nucleic acid test between July 2018 and June 2023. We used negative binomial regression to estimate reported hepatitis C incidence rate ratios by neighborhood with 95% confidence intervals (CI). A composite index score (range: 0-1) was created by ranking neighborhoods by combined social vulnerabi

SUBMITTER: Hernandez-Tamayo C 

PROVIDER: S-EPMC12903217 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature