Prevalence and incidence of infantile epileptic spasms syndrome in India: A systematic review and meta-analysis.

ABSTRACT:

Objectives

Infantile epileptic spasms syndrome (IESS) is a developmental and epileptic encephalopathy of infantile onset. While epidemiological data from Western countries and global estimates are available, consolidated evidence on the burden of IESS in India remains limited. Given India's large and diverse population, regional variations in healthcare access, diagnostic capabilities, and risk factors may significantly influence the prevalence of IESS. This systematic review and meta-analysis aimed to estimate the incidence and prevalence of IESS in India.

Methods

We conducted a comprehensive search across four electronic databases-PubMed, Embase, Scopus, and Web of Science-in May 2025 to identify studies focusing on the prevalence and incidence of IESS in Indian settings.

SUBMITTER: Singh A 

PROVIDER: S-EPMC12903817 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature