Incidence and clinical predictors of epilepsy after febrile seizures in children: A prospective cohort study in Vietnam.

ABSTRACT:

Objective

Febrile seizures (FS) are common and usually self-limited, yet a subset of children develop epilepsy. Early risk stratification remains challenging, particularly in resource-limited settings with limited access to long-term neurologic follow-up. We aimed to estimate the incidence and identify the most robust predictors of epilepsy following FS in children.

Methods

In this prospective cohort study at Children's Hospital 2 (Ho Chi Minh City, Vietnam), 631 children aged 1 month to 6 years with first FS were enrolled (March 2023-March 2024) and followed through July 2025. Children with any history of seizures prior to the index FS were excluded. Epilepsy was defined per the International League Against Epilepsy (ILAE) 2014 criteria. Predictor selection used clinical re

SUBMITTER: Bui AH 

PROVIDER: S-EPMC12903822 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature