Anti-inflammatory effects of curcumin carbon dots in an animal model of demyelination induced by lysolecithin.

ABSTRACT: Multiple Sclerosis (MS) is an autoimmune neurodegenerative disease that affects the central nervous system (CNS) characterized by myelin loss and axonal degeneration. Studies have shown that chronic inflammation followed by demyelination contributes to extensive myelin degradation. Thus far, despite disease-modifying treatments (DMTs) that delay disease progression, a definitive cure remains in demand due to the disease's uncertain etiology. Recent studies highlight carbon-based nanomaterials, particularly carbon dots (CDs), as promising drug carriers due to their antioxidant and anti-inflammatory effects, hydrophilicity, biocompatibility and fluorescence properties. In this study, curcumin-derived carbon dots (CurP-CDs) were synthesized via a one-pot hydrothermal method, and their

SUBMITTER: DaeiRezaei L 

PROVIDER: S-EPMC12903908 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature