Correlative Imaging Platform Linking Taste Cell Function to Molecular Identity.

ABSTRACT: Understanding the physiology of taste cells requires multifaceted cellular information, ranging from gene expression to functional responses. Various experimental approaches are available to obtain each biological information, such as in situ hybridization for gene transcription and in vivo microscopy for functional responses. However, correlative acquisition of genetic and functional information at the single-cell level has not yet been achieved for taste cells, limiting a comprehensive understanding of functional and genetic cell subtypes. Here, we developed a correlative imaging platform to link functional responses of taste cells to their molecular identity. This platform acquires functional imaging data and in situ hybridization or immunofluorescence data from the same region-of-inter

SUBMITTER: Lee S 

PROVIDER: S-EPMC12904051 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature