Beyond kin killing: <i>Dickeya</i>-derived phage-tail-like bacteriocin P2D1 targets phylogenetically distant <i>Pseudomonas</i> spp.

ABSTRACT: Tailocins, phage-tail-derived bacteriocins, are increasingly recognized as potent mediators of microbial antagonism, yet their ecological scope beyond kin-targeting remains poorly understood. Here, we investigated whether P2D1, a tailocin produced by the plant pathogen Dickeya dadantii 3937, can act against environmental bacteria phylogenetically distant from Dickeya spp. Screening 480 soil and rhizosphere isolates from three distinct plant-associated habitats in Poland, we identified nine Pseudomonas spp. strains susceptible to tailocin P2D1. Whole-genome sequencing and phenotype profiling revealed that these isolates spanned multiple clades, including taxa related to P. germanica, P. tensinigenes, and P. parakoreensis. The D. dadantii muta

SUBMITTER: Borowicz M 

PROVIDER: S-EPMC12904277 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature