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Association between hospital frailty risk score, risk of sepsis and adverse outcomes across all adult ages.


ABSTRACT:

Background

Hospital Frailty Risk Score (HFRS) is commonly used to identify frailty risk and predict poor outcomes. Frailty and sepsis are associated with poor outcomes. This study aimed to evaluate the association between HFRS, risk of sepsis and poor health outcomes across all adult ages.

Methods

A retrospective cohort study analysed data from Queen Alexandra Hospital, a major acute hospital in the UK, covering the period from January 1, 2010, to December 31, 2019. It included patients aged 16 and older. The Hospital Frailty Risk Score (HFRS) was used to identify patients at risk of frailty. The Suspicion of Sepsis (SOS) codes and the National Early Warning Score (NEWS) were used to identify patients at risk of sepsis. Logistic Regression with interaction models were develo

SUBMITTER: Kutrani H 

PROVIDER: S-EPMC12904455 | biostudies-literature | 2026

REPOSITORIES: biostudies-literature