Circumferential multi-contrast mapping of the aqueous outflow pathway in human eyes facilitated by circular-scan optical coherence tomography angiography.

ABSTRACT: The corneoscleral limbus contains essential aqueous channels and veins that form the primary aqueous outflow pathway, making it a critical focus of glaucoma research. Optical coherence tomography (OCT) has emerged as a powerful tool for investigating this pathway, but conventional imaging is typically performed in segments and restricted to a single functional contrast. Such approaches are limited in evaluating the overall condition of the outflow system, which contributes circumferentially asymmetrically to the aqueous outflow and is composed of multiple tissues requiring different OCT functional extensions. To address these limitations, we propose a circumferential, multi-contrast mapping framework for in vivo analysis of limbal vasculature and aqueous outflow structures/functions. The w

SUBMITTER: Gong Z 

PROVIDER: S-EPMC12904547 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature