Computational framework for combining multiple swept-sources for high-resolution in-vivo optical coherence tomography.

ABSTRACT: Axial resolution in swept-source-based Fourier-domain optical coherence tomography (FD-OCT) is limited by the sweep range of the source. However, broad swept-sources are not readily available, and passively combining two laser sources is not straightforward. In this paper, we develop a framework to overcome this limit by computationally combining independently sweeping sources to increase the bandwidth and subsequently the axial resolution of full-field Fourier-domain optical coherence tomography (FF-FD-OCT) systems. To this end, we demonstrate a dual-laser full-field FD-OCT system that uses two lasers, which sweep sequentially and are stitched phase-correctly in post-processing to obtain high-bandwidth spectra. After combining, we achieve an effective bandwidth of 145 nm at a central wave

SUBMITTER: Thakur S 

PROVIDER: S-EPMC12904556 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature