Nomenclature for Tracking of Genetic Variation of Seasonal Influenza Viruses.

ABSTRACT:

Background

Genomic surveillance of human seasonal influenza viruses is an essential component of the Global Influenza Surveillance and Response system (GISRS) and informs the recommendations for the seasonal influenza vaccine composition. Phylogenetic analysis of viral genome sequences is used to identify groups of viruses sharing potential antigenic change, and computational models are used to predict which viral variants are likely to circulate at high levels in upcoming seasons. To facilitate discussion and reporting of genetic diversity, as well as to communicate antigen recommendations, up-to-date and sufficiently granular definitions of genetic clades are important.

Methods

We implemented a nomenclature system for Segments 4 (haemagglutinin) and 6 (neuraminidase) of hu

SUBMITTER: Neher RA 

PROVIDER: S-EPMC12904685 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature