Stepwise Assessment of Computational Coronary Physiology and Plaque Vulnerability: Impact on Coronary Revascularization Decision Making.

ABSTRACT:

Background

Incremental information on coronary physiology and plaque vulnerability may improve risk stratification beyond anatomy. Murray law-based quantitative flow ratio (μFR) and radial wall strain (RWS) are angiography-derived indices for assessing coronary physiology and plaque vulnerability, but their impact on revascularization decisions remains unclear.

Objectives

The authors aimed to evaluate the impact of incremental availability of μFR and RWS on revascularization decisions.

Methods

A web-based survey was conducted, comprising 25 angiographically intermediate lesions. Data from μFR, RWS, and optical coherence tomography (OCT) were stepwisely available to participating cardiologists to make revascularization decisions (medical therapy alone or revascularizat

SUBMITTER: Li C 

PROVIDER: S-EPMC12904827 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature