Prevalence and Heterogeneity of Swine Influenza Virus in China From 2010 to 2025: A Systematic Review and Meta-Analysis.

ABSTRACT:

Background

Swine influenza virus (SIV) is endemic in China, threatening the swine industry and public health. This meta-analysis estimated the national pooled prevalence of SIV (2010-2025) and identified key sources of heterogeneity.

Methods

Following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, six databases were searched, yielding 73 eligible studies with 411,930 samples. A random-effects model pooled prevalence estimates, and subgroup analyses explored heterogeneity.

Results

The pooled SIV prevalence was 30.3% (95% confidence interval [CI]: 24.5%-36.4%) with extreme heterogeneity (I ² = 100%, p  < 0.001). Key drivers included diagnostic method (serological: 37.1% vs. virological: 2.6%), geography (

SUBMITTER: Yang X 

PROVIDER: S-EPMC12904846 | biostudies-literature | 2026

REPOSITORIES: biostudies-literature