Cognitive impairment, depression, and fatigue in post-COVID and post-vaccination syndrome: a large-scale cross-sectional study.

ABSTRACT:

Background

Persistent cognitive difficulties are among the most prevalent symptoms observed after COVID-19. This study examined the neuropsychological characteristics, mental health and risk factors associated with cognitive impairment in patients with Post-Acute Sequelae of COVID-19 (PASC). In addition, differences regarding the cognitive dysfunctions between individuals with PASC and Post-Vaccination Syndrome (PVS) were explored.

Methods

Participants were consecutively recruited at the Post-COVID Center of the University Hospital Erlangen in Germany (12/2022-02/2025). Assessments included a broad neuropsychological assessment: d2 Test of Attention, digit span backwards from the Wechsler Memory Scale-Revised (WMS-R) and module 1 (formal lexical fluency) of the Regensburger

SUBMITTER: Hanc E 

PROVIDER: S-EPMC12904920 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature