Characterization, in-vitro biological and antimicrobial testing of replacing Sr/Ca in wollastonite (Ca<sub>1 - x</sub> Sr<sub>x</sub> SiO<sub>3</sub>) glass-ceramics.
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ABSTRACT: Strontium-doped wollastonite glass-ceramics with varying Sr concentrations (0.125, 0.25, and 0.50 wt%) were successfully synthesized via a melt-quenching technique and comprehensively evaluated for structural, physical, and biological performance, including in vitro biocompatibility, antimicrobial activity, and cytotoxicity. Characterization using DTA, XRD, and FE-SEM/EDX confirmed progressive hydroxyapatite (HA) formation following 28 days of immersion in simulated body fluid (SBF), with XRD revealing a reduction in wollastonite peaks and distinct HA signals, particularly in Sr-containing samples. FTIR spectra showed intensified phosphate absorption bands, while FE-SEM/EDX analyses highlighted a morphological shift from plate-like structures to needle-like HA crystals. Strontium doping wa
SUBMITTER: El-Hamid HKA
PROVIDER: S-EPMC12905248 | biostudies-literature | 2026 Feb
REPOSITORIES: biostudies-literature
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