Sequence-encoded layered heteroleptic metalla-[2]catenanes for programmable supramolecular function.

ABSTRACT: Molecular information encoded within supramolecular frameworks offers a powerful paradigm for directing emergent function beyond the genetic code, but systematic investigations into alternative spatial configurations and their consequences remain scarce. Here we use metalla-[2]catenanes to probe sequence-function relationships in layered architectures. By combining two or three size-matched N-heterocyclic carbene ligands with Ag(I) nodes, we selectively construct heteroleptic metalla-[2]catenanes through both direct assembly and supramolecular fusion pathways. X-ray crystallographic analysis unambiguously confirms the targeted sequences, while semiempirical and density functional theory calculations reveal their thermodynamic preference over alternative isomers. Photothermal conversion stu

SUBMITTER: Zhang YW 

PROVIDER: S-EPMC12905427 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature