Safety of laparoscopic oophorectomy in a Dutch national pediatric cancer cohort.

ABSTRACT:

Objective

To report our experiences on the safety of laparoscopic oophorectomy (LO) for ovarian tissue cryopreservation in childhood cancer (CC) patients.

Design

Descriptive study of a prospectively registered cohort.

Subjects

All CC patients undergoing LO in the Netherlands from November 2020 until April 2024.

Exposure

Laparoscopic oophorectomy for means of fertility preservation before or during gonadotoxic treatment.

Main outcome measures

Safety, including procedure-related complications, such as critical events (desaturation, bradycardia), need for mechanical ventilation in a pediatric intensive care unit (PICU), site infections, hemorrhage, and survival, scored according to Clavien Dindo (CD) classification.

Results

Eighty-eight patients, med

SUBMITTER: Clasen NHZ 

PROVIDER: S-EPMC12905605 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature