Human Milk and Infant Gut Microbiome in Association With Infant Fecal Metabolome and Child Blood Pressure.

ABSTRACT:

Importance

Infant milk feeding type (eg, human milk vs formula) and infant gut microbes have each been associated with differences in microbial metabolites and childhood blood pressure; however, evidence remains limited regarding how specific infant gut microbes, at a species or strain level, in combination with milk feeding type, shape microbial metabolites and blood pressure.

Objective

To investigate whether human milk feeding and infant gut microbes, including Bifidobacterium longum subsp infantis (B infantis) and other milk-degrading microbes, are associated with infant fecal metabolites and childhood systolic blood pressure (SBP).

Design, setting, and participants

This cohort study was part of the Canadian Healthy Infant Longitudinal Development (CHILD) cohort st

SUBMITTER: Liu T 

PROVIDER: S-EPMC12905658 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature