Whole genome analysis of carbapenem resistant <i>Acinetobacter baumannii</i> isolates from healthcare-associated infections in Dakar, Senegal.

ABSTRACT:

Background

Carbapenem resistant Acinetobacter baumannii (CRAB) is considered a top priority pathogen by the World Health Organization and is also considered a leading cause of healthcare-associated infections (HAIs). This study aimed to investigate antimicrobial resistance (AMR) patterns and perform comprehensive whole-genome analysis on CRAB strains isolated from HAIs in Dakar, Senegal.

Methods

CRAB isolates were collected from 2018 to 2021 in two major hospitals in Dakar and subjected to antimicrobial susceptibility tests followed by whole genome sequencing and comprehensive bioinformatic analysis to identify resistance genes, mobile genetic elements (MGEs) and perform phylogeny analysis.

Results

The isolates demonstrated an alarming level of resistance to mu

SUBMITTER: Ndiaye I 

PROVIDER: S-EPMC12905747 | biostudies-literature | 2026 Apr

REPOSITORIES: biostudies-literature