The Occipital-Fronto-Limbic Circuit of Body Dysmorphic Disorder: A Systematic Review and Meta-Analysis of Neuroimaging Studies.

ABSTRACT:

Background

Body dysmorphic disorder (BDD) is a severe psychiatric disorder characterized by excessive preoccupation with perceived flaws in appearance. In this review, we aim to synthesize the latest findings on the neurobiology of BDD and propose an updated BDD neurocircuitry model.

Methods

A systematic search identified 38 peer-reviewed original articles, and the protocol was registered (CRD42024553665). Qualitative thematic analysis was conducted, and activation likelihood estimation (ALE) meta-analysis was performed to quantify brain activation patterns.

Results

Brain regions with significant morphometric divergence in patients with BDD were predominantly located in primary and secondary visual processing areas and temporal-limbic and frontal-striatal networks des

SUBMITTER: Cheng Y 

PROVIDER: S-EPMC12905759 | biostudies-literature | 2026 Mar

REPOSITORIES: biostudies-literature